What is Acrodermatitis Enteropathica?
(Symptoms, Causes & Treatment)
According to the U.S. National Library of Medicine, acrodermatitis enteropathica is a rare genetic autosomal recessive disorder, characterized by periorificial dermatitis, alopecia, and diarrhea. It is caused by mutations in the gene that encodes a membrane protein that binds zinc. Acrodermatitis enteropathica is also called acrodermatitis enteropathy, primary zinc malabsorption syndrome, Danbolt-Closs syndrome and Brandt syndrome.
Symptoms usually occur in bottle-fed infants within a few days or weeks after birth and breast-fed infants soon after weaning. Both males and females are equally affected.
The acquired form of this disorder generates similar symptoms. One transient form can result from failure of the mother to secrete zinc into her breast milk. Other acquired forms of AE sometimes result after surgery to bypass some of the upper intestine or from special intravenous nutritional programs that are prepared without the appropriate amount of zinc.
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Latest Acrodermatitis Enteropathica Treatment News and Research
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