Amyloidosis Treatment News and Information

What is Amyloidosis? (Definition)

Amyloidosis is a group of diseases that are a result of abnormal proteins deposits in different parts of the body. This protein is called Amyloid. There are over 30 different kinds of amyloid proteins. This causes severe changes in the organ that Amyloid is present in. There are three major separations of amyloidosis. According to medicinenet.com, the major types of systemic amyloidosis are currently categorized as primary (AL), secondary (AA), and hereditary (ATTR, amyloid apolipoprotein A1 or AApoAI, amyloid apolipoprotein A2 or AApoAII, AGel, ALys, AFib).

Eventually the amyloid proteins deposits cause organ failure. Since the disease is so rare doctors and researchers are constantly finding out new things. Roughly between 1,500 and 2,500 people develop AL Amyloidosis each year in the United States.

Symptoms include irregular function of the specific organ targeted by Amyloidosis. There is currently no cure for Amyloidosis. However treatments can help signs and symptoms and possibly limit the production of amyloid protein.

Tests and Diagnosis

  • Laboratory Tests
  • Biopsy
  • Imagining Tests

See below for updated news and information regarding Amyloidosis including new research, treatments and advancements. 

Latest Amyloidosis News

With Promising Results from Emerging Therapies, Penn Research Yields Fresh Hope for Treatment of Rare Disease AL Amyloidosis

(SOURCE: UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE): Amyloidosis Research News: Two new treatments are showing promise and overall survival is on the rise for AL amyloidosis, according to a series of studies involving researchers in the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania. They will present their findings at this week’s 58th Annual ...
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Pomalidomide + Dexamethasone Rescue Active in AL Amyloidosis

Cancer Therapy AdvisorJan 30, 2017
Rescue therapy with pomalidomide in combination with dexamethasone is a rapidly active regimen in amyloid light-chain (AL) amyloidosis.
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Amyloidosis: A puzzle for both patients and doctors

Pittsburgh Post-GazetteSep 19, 2016
Darcy Tannehill is being treated for amyloidosis, the disease that claimed the lives of Mayor Richard S. Caliguiri and Gov. Robert P. Casey.
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With promising results from emerging therapies, research yields

Science DailyDec 1, 2016
Immunoglobulin light-chain amyloidosis (AL) is a rare, life-threatening disease that occurs when toxic proteins build up in organs, which alters …
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Bortezomib-Based Chemo Ups Survival in AL Cardiac Amyloidosis

MedscapeJun 29, 2016
AL amyloidosis results from a plasma-cell dyscrasia that causes unchecked production of a monoclonal immunoglobulin light chain.
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Amyloidosis Treatments Miss the Heart of the Problem

MedPage TodayDec 7, 2016
SAN DIEGO – Treatments aimed at patients diagnosed with amyloidosis fail to get to the root of the problem — improving function of organs …