Atherosclerosis Treatment News and Information

What is Atherosclerosis? (Definition)

Atherosclerosis (also known as arteriosclerotic vascular disease or ASVD) is a disease in which plaque builds up inside your arteries which can lead to serious problems, including heart attack, stroke, or even death. Because Atherosclerosis can affect any artery in the body (including main arteries located in the heart, brain, kidneys, arms, legs, and pelvis), different diseases may develop based on which arteries are affected. These diseases can include Carotid Artery Disease, Coronary Heart Disease, Peripheral Artery Disease, and Chronic Kidney Disease.

Atherosclerosis begins when the endothelium becomes damaged, allowing LDL cholesterol to accumulate in the artery wall. Endothelium is a thin layer of cells that keeps the artery smooth and allows blood to flow. 

There is no known specific cause of Atherosclerosis, however, certain traits, conditions, or habits may raise your risk for the disease. Controllable conditions include such things as lack of physical activity, smoking, and an unhealthy diet. Other non-controllable conditions are thought to include age and a family history of heart disease.

Symptoms and Signs of Atherosclerosis

Atherosclerosis is asymptomatic (shows no symptoms) for decades because the arteries enlarge at all plaque locations, so there is no noticeable effect on blood flow. Even most plaque ruptures do not produce symptoms until enough narrowing or closure of an artery, due to clots, occurs. Signs and symptoms only occur after severe narrowing or closure impedes blood flow to different organs enough to induce symptoms. Most of the time, patients realize that they have the disease only when they experience other cardiovascular disorders such as stroke or heart attack. These symptoms, however, still vary depending on which artery or organ is affected. If you are noticing symptoms similar to those of heart disease, coronary artery disease, or kidney disease, it’s very important to get checked out by your doctor or healthcare professional. 

See below for updated news and information regarding Atherosclerosis including new medical research, treatment options and advancements. 

Latest Atherosclerosis Treatment News and Research

Atherosclerosis Treatment News: Endogenous peptide lowers cholesterol

(SOURCE: LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN) - Cells of the innate immune system that play an important role in development of atherosclerosis contain a protein that reduces levels of cholesterol in mice – and thus helps to inhibit or mitigate the disease. Atherosclerosis remains one of the primary causes of premature death in modern Western societies. The term itself refers to insoluble, fat-rich deposits that ...
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New Guidelines for Treatment of Peripheral Artery Disease

(AMERICAN HEART ASSOCIATION) According to a recent press release, new guidelines for the treatment of peripheral artery disease (PAD), include recommendations on the use of antiplatelet therapy to reduce the risk of blood clots and statin drugs to lower cholesterol and advise PAD patients to participate in a structured exercise program ...
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Link Found Between Senescent Cells and Atherosclerosis Progression

(Mayo Clinic) According to a recent Mayo Clinic press release, atherosclerosis is a disease in which arteries narrow due to plaques. That narrowing can lead to heart attacks and strokes -- both of which are leading causes of death in the U.S. Now, in a paper published in Science, Mayo Clinic researchers and colleagues show that senescent cells drive plaque ...
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Researchers Identified Two PARP Proteins as Regulators of Macrophage Activation in Development of Atherosclerosis

(BRIGHAM AND WOMEN'S HOSPITAL) According to a recent press release from Brigham and Women's Hospital, researchers have found two new potential drug targets for treating arterial diseases such as atherosclerosis. By using proteomics to screen a vast number of molecules, the researchers identified PARP9 and PARP14 - two members of the PARP family of proteins - as regulators of macrophage activation, ...
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