What is Canavan Disease? (Definition)
(Symptoms, Causes & Treatment)
According to the U.S. National Library of Medicine, Canavan disease is a rare inherited disorder or condition which damages the ability of neurons (nerve cells) in the brain to send and receive messages. This disease is one of a group of genetic disorders called leukodystrophies which disrupt the growth or maintenance of the myelin sheath, which is the covering that protects nerves and promotes the efficient transmission of nerve impulses.
Neonatal/infantile Canavan disease is the most common form of Canavan disease and is also the most severe. Affected infants appear normal for the first few months of life, but by age 3 to 5 months, problems with development become noticeable. These infants usually do not develop motor skills such as turning over, controlling head movement, and sitting without support. Other common features and signs include weak muscle tone (hypotonia), an unusually large head size (macrocephaly), and irritability. Feeding and swallowing difficulties, seizures, and sleep disturbances may also develop.
See below for updated news and information regarding Canavan Disease including new medical research, treatment options and advancements.
Latest Canavan Disease Research – Treatment News, Discoveries and Findings
No recent news regarding Canavan Disease is available.
Clinical Resources: Treatment Therapies & Guidelines
Clinical Trials – Investigational Therapies
For information on current clinical trials, visit www.clinicaltrials.gov. This is a searchable registry and results database of federally and privately supported clinical trials taking place in the U.S and abroad. ClinicalTrials.gov provides information about a trial’s purpose, who may participate, locations, and phone numbers. This information should be used in conjunction with advice from health care professionals.
For information about clinical trials being conducted at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD, contact the NIH Patient Recruitment Office:
Toll Free: (800) 411-1222
TTY: (866) 411-1010
For information about clinical trials conducted in Europe, visit: https://www.clinicaltrialsregister.eu/ctr-search/search
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