Health Medical Breakthroughs Treatment

‘Sweet Spot’ for Additional Breast Imaging Found

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: RUSH UNIVERSITY MEDICAL CENTER) – Breast cancer detection increases significantly when radiologists recall mammogram patients for additional imaging more often than recommended by the current guidelines, according to a study by a radiologist at Rush. The study determined that the “sweet spot” for finding breast cancer is in the recall range of 12 to 14 percent, compared […]

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Big data brings breast cancer research forwards by ‘decades’

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: CANCER RESEARCH UK) – Scientists have created a ‘map’ linking the shape of breast cancer cells to genes turned on and off, and matched it to real disease outcomes, which could one day help doctors select treatments, according to a study published in Genome Research today (Wednesday).* In a revolutionary new approach, Cancer Research UK-funded scientists […]

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Breast Cancer Treatment News: Natural compound could improve treatment of triple-negative breast cancer

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: UNIVERSITY OF MISSOURI-COLUMBIA) – More than 100 women die from breast cancer every day in the United States. Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast disease that often metastasize to distant sites. Now, University of Missouri researchers have found that luteolin, a natural […]

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Timing of chemo affects inflammation, mice study suggests

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: THE OHIO STATE UNIVERSITY) – Finding ‘sweet spot’ for drug administration could help patients. The time of day that breast cancer chemotherapy drugs are given affects the amount of damaging inflammation in the body, a new study in mice suggests. That’s important because inflammation, particularly in the brain, is believed to contribute to many of […]

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Breast Cancer Research Findings: Breast Cancer Prognosis of African-American Patients May Improve with Administration of Chemotherapy Before Surgery, Study Finds

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: GEORGIA STATE UNIVERSITY) – Administering chemotherapy to African-American breast cancer patients prior to surgery could improve their prognosis and survival rates from the disease, according to a new study. A research team led by Georgia State University found African-American breast cancer patients who receive chemotherapy prior to surgery exhibit trends of reduced regional (in lymph nodes) […]

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Breast Cancer Research: Protein identified by Mass. General team may protect tumor-initiating cells in breast cancer

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: MASSACHUSETTS GENERAL HOSPITAL) – Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) – treatment-resistant cells responsible for cancer recurrence and metastasis – in breast cancer, as well as a compound that appears to reduce the molecule’s ability to protect TICs from […]

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Breast Cancer Treatment News: Mayo Clinic researchers identify new potential treatment for cancer metastasis

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: MAYO CLINIC) – Breast cancer metastasis, the process by which cancer spreads, may be prevented through the new use of a class of drugs already approved by the U.S. Food and Drug Administration. Mayo Clinic researchers have identified that a key drug target, CDK4/6, regulates a cancer metastasis protein, SNAIL, and drugs that inhibit CDK […]

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Metaplastic Breast Cancer Treatment Research: ACCELERATED RESEARCH DISCOVERY A TRIPLE THREAT TO TRIPLE NEGATIVE BREAST CANCER

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: HOUSTON METHODIST) – Houston Methodist Hospital researchers have advanced a potential treatment for metaplastic breast cancer—the most aggressive subtype of triple negative breast cancer, into patients in just under four years.  In a study published in the Journal of the National Cancer Institute (early online Dec. 31), a multi-institutional team led by Jenny C. Chang, M.D., […]

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Breast Cancer Treatment Research: Vaccine Shows Promising Results for Early-Stage Breast Cancer Patients

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: MOFFITT CANCER CENTER) – Immunotherapy is a fast growing area of cancer research. It involves developing therapies that use a patient’s own immune system to fight and kill cancer. Moffitt Cancer Center is working on a new vaccine that would help early-stage breast cancer patients who have HER2 positive disease. The HER2 protein is overexpressed […]

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Scripps Florida Scientists Develop Drug Discovery Approach to Predict Health Impact of Endocrine-Disrupting Chemicals

Posted on Posted in Breast Cancer News, Women's Health News

(SOURCE: SCRIPPS RESEARCH INSTITUTE) – Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer. Environmental estrogens work by binding to the estrogen receptor, a protein in cells […]

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Breast Cancer Treatment Research: Nanoparticles Could Help Overcome Treatment-Resistant Breast Cancer

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: UNIVERSITY OF CINCINNATI ACADEMIC HEALTH CENTER) – Researchers at the University of Cincinnati (UC) College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients. The study, published in the Dec. 14, 2016, online edition of American Chemical Society’s […]

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Enzyme that regulates DNA repair may offer new precision treatments for breast and ovarian cancer

Posted on Posted in Breast Cancer News, Ovarian Cancer

(SOURCE: MAYO CLINIC) Researchers at Mayo Clinic have identified an enzyme called UCHL3 that regulates the BRCA2 pathway, which is important for DNA repair. Results of this research are published online in Genes & Development. “DNA encodes the blueprints for our body, and DNA repair is a fundamental mechanism to prevent the accumulation of mutations in […]

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Breast Cancer Research: Study reveals drug interactions that may reduce mortality in breast cancer patients

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: STANFORD UNIVERSITY MEDICAL CENTER) – Stanford researchers found that certain drug combinations were associated with lower mortality rates among breast cancer patients, pointing to potential drug targets and new ways of thinking about known diseases. Patient health records revealed two drug combinations that may reduce mortality rates in breast cancer patients, according to a study led […]

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Breast Cancer Research News: Image-guided biopsy identifies patients who achieve pathologic complete response after neoadjuvant therapy

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER) – Select groups of invasive breast cancer patients may be able to avoid surgery in future. In a pilot study conducted at The University of Texas MD Anderson Cancer Center, image-guided biopsies identified select breast cancer patients who achieved pathologic complete response (pCR) after chemotherapy and/or targeted therapy, […]

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Breast Cancer News: Older women with breast cancer report better cosmetic satisfaction with less radiation, less surgery

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER) – In the first study evaluating patient-reported cosmetic outcomes in a population-based cohort of older women with breast cancer, The University of Texas MD Anderson Cancer Center researchers found that less radiation was associated with improved cosmetic satisfaction long-term. However, reduced radiation was also associated with a slightly […]

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Breast Cancer Treatment Research: Radiation Therapy May Increase Complications in Breast Cancer Patients Receiving Implants

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: AMERICAN ASSOCIATION FOR CANCER RESEARCH) – Radiotherapy increased complications and impaired patient-reported satisfaction with reconstructed breasts in breast cancer patients who received implant reconstruction but not in those who received autologous reconstruction, according to data from a large, prospective, multicenter cohort study presented at the 2016 San Antonio Breast Cancer Symposium, held Dec. 6–10. Autologous breast […]

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Breast Cancer Research: New Study Shows Targeted Therapy Needed for Breast Cancer with Brain Metastases

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: UNIVERSITY OF PITTSBURGH SCHOOLS OF THE HEALTH SCIENCES) – Researchers at the University of Pittsburgh Cancer Institute(UPCI) and Magee-Womens Research Institute (MWRI) have discovered molecular changes in the primary tumor of breast cancer patients who developed brain metastases. The finding is expected to lead to improved diagnosis and targeted therapies. The results, to be published in […]

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Breast Cancer Research News: Mayo Clinic research helps refine role of gene variants in breast cancer risk

Posted on Posted in Breast Cancer News, Cancer News

(SOURCE: MAYO CLINIC) – Inherited pathogenic variants in protein coding genes BARD1 and RAD51D increase a woman’s likelihood of developing breast cancer, according to research conducted at Mayo Clinic and presented today at the 2016 San Antonio Breast Cancer Symposium. Pathogenic variants are changes in DNA that have a negative impact on a gene’s ability to function properly. […]