(SOURCE: VIRGINIA TECH) – Could inflammatory bowel disease and colon cancer be prevented by changing the shape of a single protein? There is an intimate link between uncontrolled inflammation in the gut associated with inflammatory bowel disease and the eventual development of colon cancer. This uncontrolled inflammation is associated with changes in bacteria populations in the […]
(SOURCE: GEORGIA STATE UNIVERSITY) – An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study. Researchers at Georgia State […]
(SOURCE: MAYO CLINIC) – Mayo Clinic researchers and a team of collaborating scientists from across the country have determined the comparative effectiveness of nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin and several supplements in preventing the recurrence of advanced neoplasia (polyps that are the precursor of colorectal cancer) after polyp removal. According to the World Cancer Research […]
(SOURCE: St. Jude Children’s Research Hospital) – St. Jude Children’s Research Hospital researchers and collaborators reveal how a tumor-suppressing protein interacts with genetic enhancers to silence cancer genes in a newly developed model system. A team of scientists has developed a model system in mice that allows them to look closely at how a protein often mutated […]
(SOURCE: ST. JUDE CHILDREN’S RESEARCH HOSPITAL) – St. Jude Children’s Research Hospital scientists tracking the protective role of the protein called NLRC3 have discovered multiple targets for drugs to switch on the cell’s machinery to thwart colon cancer. Immunologists at St. Jude Children’s Research Hospital have discovered that a protein called NLRC3 plays a central role […]
(SOURCE: McGill University) – Just four weeks of prehabilitation (pre-surgery preparation) may be enough to help some cancer patients get in shape for surgery. That’s according to a recent study of close to 120 colorectal cancer patients in Montreal. This potentially means that, barring unforeseen circumstances that stem from the surgery itself, their recovery is likely […]
(UNIVERSITY OF ILLINOIS AT CHICAGO) According to a recent press release, researchers at the University of Illinois at Chicago have identified a new way to block the action of genetic mutations found in nearly 30 percent of all cancers.
(UT SOUTHWESTERN MEDICAL CENTER) According to a recent press release, a small molecule called TASIN-1 can selectively kill cells with a mutation that is considered to be a precursor to colon cancer, while sparing related normal cells, UT Southwestern Medical Center cancer biologists have demonstrated.
(THE JAMA NETWORK JOURNALS) According to a recent press release, a new report published online by JAMA Oncology reviewed medical literature to examine the prognostic role of a primary colon cancer tumor being located on the left vs. right side.
(BOSTON UNIVERSITY MEDICAL CENTER) According to a recent press release, researchers from Boston University School of Medicine (BUSM) have discovered a possible strategy to treat colon cancers that are caused by the mutant KRAS gene, which is responsible for approximately half of all colon cancer cases.
(PRNewswire) According to a press release, Boston Biomedical recently announced dosing of the first patient in CanStem303C, a new global Phase III study investigating napabucasin in combination with standard of care (FOLFIRI) in patients with previously treated metastatic colorectal carcinoma (mCRC).