Health Medical Breakthroughs Treatment

Leukemia Diagnosis Research News: Advances prompt release of new recommendations for diagnosis, management of adult AML

Posted on Posted in Cancer News, Leukemia News

(SOURCE: OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER) – An international panel of experts has released updated evidence-based and expert-opinion-based recommendations for the diagnosis and treatment of acute myeloid leukemia (AML) in adults. The recommendations were issued by the European LeukemiaNet (ELN) and published in the journal Blood. The paper’s senior author was Clara D. Bloomfield, MD, Distinguished […]

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Leukemia Treatment Research News: Research leads to new treatment recommendations for a high-risk pediatric leukemia

Posted on Posted in Cancer News, Leukemia News

(SOURCE: ST. JUDE CHILDREN’S RESEARCH HOSPITAL) – International researchers led by St. Jude Children’s Research Hospital have identified genetic alterations that can be used to guide treatment of pediatric acute megakaryoblastic leukemia, which has a dismal prognosis. Research led by St. Jude Children’s Research Hospital has identified three genetic alterations to help identify high-risk pediatric patients with […]

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Leukemia Lymphoma Treatment Research Shows Promise: New drug cocktail unlocks potential of new Leukaemia treatment

Posted on Posted in Cancer News, Leukemia News, Lymphoma News

(SOURCE: UNIVERSITY OF MANCHESTER) – A new combination of drugs, tested by University of Manchester scientists, has significantly enhanced the survival of laboratory mice with lymphoma. According to the team, the effect of Obinutuzumab – a first-line treatment for non-Hodgkin lymphoma and leukaemia – is significantly enhanced when combined with drugs that stimulate the immune system. […]

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Acute Myeloid Leukaemia Treatment News: Researchers from Goethe University discover a new clinical biomarker to improve treatment of leukemia

Posted on Posted in Cancer News, Leukemia News

(SOURCE: GOETHE UNIVERSITY FRANKFURT) – Because it is impossible to predict which acute myeloid leukaemia (AML) patients will benefit, all patients are routinely treated with chemotherapy although only some will respond to the treatment. Researchers from Goethe-University Frankfurt have now discovered a novel biomarker that enables the detection of therapy responders and non-responders with high accuracy. In […]

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Mixed Lineage Leukemia Research: Halting Lethal Childhood Leukemia

Posted on Posted in Cancer News, Leukemia News

(SOURCE: NORTHWESTERN UNIVERSITY) – Scientists identify molecular therapy to prevent growth of pediatric leukemia. Northwestern Medicine scientists have discovered the genetic driver of a rare and lethal childhood leukemia and identified a targeted molecular therapy that halts the proliferation of leukemic cells. The finding also has implications for treating other types of cancer. Mixed lineage leukemia (MLL) […]

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Myelodysplastic Syndrome Treatment Research: Possible Treatment Targets Found for Pre-Malignant Bone Marrow Disorders

Posted on Posted in Leukemia News, Myelodysplastic Syndromes News

(SOURCE: CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER) – Cincinnati Children’s researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS) – a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells. MDS can lead to acute myeloid leukemia (AML), […]

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Leukemia Research News – Obesity-Associated Protein Could Be Linked to Leukemia Development

Posted on Posted in Cancer News, Leukemia News

(SOURCE: UNIVERSITY OF CINCINNATI ACADEMIC HEALTH CENTER) – Cancer researchers at the University of Cincinnati have found an obesity-associated protein’s role in leukemia development and drug response which could lead to more effective therapies for the illness. The study, published in the Dec. 22 online edition of Cancer Cell and led by Jianjun Chen, PhD, associate professor […]

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Leukemia Research News: Fasting kills cancer cells of most common type of childhood leukemia

Posted on Posted in Cancer News, Leukemia News

(SOURCE: UT SOUTHWESTERN MEDICAL CENTER) – UT Southwestern Medical Center researchers have found that intermittent fasting inhibits the development and progression of the most common type of childhood leukemia. This strategy was not effective, however, in another type of blood cancer that commonly strikes adults. “This study using mouse models indicates that the effects of fasting on blood […]

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Leukemia – Multiple Myeloma Research News: AGGRESSIVE FORM OF LEUKEMIA LINKED TO DEFECTIVE ‘PROTEIN FACTORY’

Posted on Posted in Cancer News, Leukemia News, Multiple Myeloma

(SOURCE: KU LEUVEN) – Twenty to forty percent of the patients with the type of leukaemia known as multiple myeloma have a defect in the ‘protein factory’ of the cell: the ribosome. These patients have a poorer prognosis than patients with intact ribosomes. At the same time, they respond better to a drug that already exists. These are the findings […]

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Leukemia Research News: The quest to better understand the deadliest childhood leukemia

Posted on Posted in Cancer News, Leukemia News

(SOURCE: FRED HUTCHINSON CANCER RESEARCH CENTER) – Oncologists are beginning to leverage unique genomic characteristics of pediatric AML to improve treatment and prognosis. By Sabrina Richards / Fred Hutch News Service Acute myeloid leukemia is the deadliest leukemia among children. Only half of patients will achieve long-term remission. But scientists see change on the horizon. Taking advantage of […]

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Leukemia Research: Two Genetic Mutations Discovered in Subset of Acute Myeloid Leukemia

Posted on Posted in Cancer News, Leukemia News

(SOURCE: OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER) – Two genetic mutations known to play a role in many solid cancers might also help explain why a subset of acute myeloid leukemia (AML) patients develop the disease, according to new research from The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. […]

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Leukemia Research News: IKZF1 Gene Mutations Found to Increase Hereditary Risk for Acute Lymphocytic Leukemia in Children

Posted on Posted in Cancer News, Leukemia News

(SOURCE: AMERICAN SOCIETY OF HEMATOLOGY) – An abstract presented  during the 58th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego identifies inherited genetic mutations in the gene IKZF1 that confer a higher likelihood of developing pediatric acute lymphocytic leukemia (ALL). The findings are among the latest evidence to point to a strong inherited genetic basis […]

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Leukemia Treatment Research News: Side effects of leukemia drug can be safely reduced by halving dose

Posted on Posted in Cancer News, Leukemia News

(SOURCE: UNIVERSITY OF LIVERPOOL) – Patients with a chronic type of leukaemia could safely reduce the side effects of life-long treatment by cutting their dose in half, according to the results of a University of Liverpool led study presented at an international conference in America this week. Drugs known as tyrosine kinase inhibitors (TKI) have drastically improved […]

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Highlights include first results of multisite trial of CTL019 for pediatric acute lymphoblastic leukemia and new CAR T cell therapy for multiple myeloma

Posted on Posted in Cancer News, Leukemia News, Multiple Myeloma

(SOURCE: UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE) Lymphoma and Multiple Lyeloma Research News – Researchers from the Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia (CHOP) will present the latest advances from their studies of personalized cellular therapies for blood cancers during the 58th Annual Meeting of the American […]

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Leukemia Treatment News: Cancer Gene Predicts Treatment Response In Highly Lethal Type of Leukemia

Posted on Posted in Cancer News, Leukemia News

(WASHINGTON UNIVERSITY SCHOOL OF MEDICINE) According to a recent press release, patients with the most lethal form of acute myeloid leukemia (AML) – based on genetic profiles of their cancers – typically survive for only four to six months after diagnosis, even with aggressive chemotherapy. But new research indicates that such patients, paradoxically, may live […]

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Leukemia Treament News: Researchers Hopeful that Creation of First Mouse Model for Lymphoblastic Leukemia Could Speed Up Development and Testing of New Drug Therapies

Posted on Posted in Leukemia News

(UNIVERSITY OF CHICAGO MEDICAL CENTER) According to a recent press release, after nearly two decades of unsuccessful attempts, researchers from the University of Chicago Medicine and the Cincinnati Children’s Hospital Medical Center have created the first mouse model for the most common form of infant leukemia. Their discovery, published in the Nov. 14, 2016, issue […]

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Leukemia News: Potential Targeted Therapy Found for Newly Identified High-Risk Leukemia Subtype

Posted on Posted in Cancer News, Leukemia News

(ST. JUDE CHILDREN’S RESEARCH HOSPITAL) According to a recent press release, an international research team led by St. Jude Children’s Research Hospital investigators has uncovered details of a new, high-risk subtype of acute lymphoblastic leukemia (ALL) as well as a possible targeted therapy. The findings appear today in the scientific journal Nature Communications.

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Researchers Discover Cell Molecule CD98 Promotes Acute Myeloid Leukemia and Blocking May Offer New Hope

Posted on Posted in Cancer News, Leukemia News

(UNIVERSITY OF CALIFORNIA – SAN DIEGO) According to a press release, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes acute myeloid leukemia (AML). The study, published October 27 by Cancer Cell, also shows that inhibiting CD98 with the therapeutic antibody […]