Health Medical Breakthroughs Treatment

Screening with frequent personalized CA125 testing may improve detection of ovarian cancer in high-risk women

Posted on Posted in Cancer News, Ovarian Cancer

(SOURCE: MASSACHUSETTS GENERAL HOSPITAL) – The combined results of two ovarian cancer screening trials suggest that a personalized strategy involving frequent screening of high-risk women could improve the chance that tumors are detected at early stages when they are easier to treat. As reported in a paper published in Clinical Cancer Research, these trials imply that a […]

Health Medical Breakthroughs Treatment

Ovarian Cancer Treatment News: Murine study finds potential boost for ovarian cancer drug Olaparib

Posted on Posted in Cancer News, Ovarian Cancer

(SOURCE: ROCKEFELLER UNIVERSITY PRESS) – Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza). Their findings in the study “Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair […]

Health Medical Breakthroughs Treatment

Ovarian Cancer Treatment News: New test could detect ovarian cancer patients who are strongly responding to treatment

Posted on Posted in Cancer News, Ovarian Cancer

(SOURCE: CANCER RESEARCH UK) – Scientists might be able to quickly predict how ovarian cancer patients are likely to respond to chemotherapy treatment using a simple blood test, according to a Cancer Research UK-funded study published in PLOS Medicine. In a study of 40 patients with high grade serous ovarian cancer, the researchers monitored tumour DNA […]

Health Medical Breakthroughs Treatment

Enzyme that regulates DNA repair may offer new precision treatments for breast and ovarian cancer

Posted on Posted in Breast Cancer News, Ovarian Cancer

(SOURCE: MAYO CLINIC) Researchers at Mayo Clinic have identified an enzyme called UCHL3 that regulates the BRCA2 pathway, which is important for DNA repair. Results of this research are published online in Genes & Development. “DNA encodes the blueprints for our body, and DNA repair is a fundamental mechanism to prevent the accumulation of mutations in […]

Health Medical Breakthroughs Treatment

Ovarian Cancer News: Study Finds that a Combination Therapy improves Chemoresistance

Posted on Posted in Cancer News, Ovarian Cancer

(THE WISTAR INSTITUTE) According to a recent press release, treating ovarian cancer with platinum-based chemotherapy drugs such as cisplatin is initially very effective, with about four out of five patients responding favorably. However, most of these patients quickly become resistant to chemotherapy and may not respond as well to this standard treatment for the disease.

Health Medical Breakthroughs Treatment

Experimental Immunotherapy Galinpepimut-S May Benefit Multiple Myeloma Patients

Posted on Posted in Cancer News, Leukemia News, Mesothelioma, Multiple Myeloma, Ovarian Cancer

(Myeloma Research News) According to a recent article published Myeloma Research News, patients with high-risk multiple myeloma may benefit from an experimental immunotherapy from SELLAS Life Sciences called galinpepimut-S, following an autologous stem cell transplant (ASCT). The data was gathered from a Phase 2 clinical trial which shows that the agent nearly doubles the progression-free survival rates […]

Health Medical Breakthroughs Treatment

Oxford Gene Technology Simplifies Detection of Important Cancer Gene Variants

Posted on Posted in Breast Cancer News, Cancer News, Ovarian Cancer

(PR Newswire) Oxford Gene Technology (OGT), The Molecular Genetics Company, has launched its SureSeq myPanel™ NGS Custom Cancer Panels to provide scientists with completely customized, pre-optimized next generation sequencing (NGS) probe panels relevant to their research. The comprehensive library of gene content covers key cancer types including, myeloid, chronic lymphocytic leukemia (CLL), ovarian and breast. Utilizing hybridisation-based capture, […]