(SOURCE: SALK INSTITUTE) – Just as an invasive weed might need nutrient-rich soil and water to grow, many cancers rely on the right surroundings in the body to thrive. A tumor’s microenvironment—the nearby tissues, immune cells, blood vessels and extracellular matrix—has long been known to play a role in the tumor’s growth. Now, Salk scientists have pinned […]
(SOURCE: UNIVERSITY OF MICHIGAN HEALTH SYSTEM) – A protein thought to fuel pancreatic cancer development plays a much more complicated role, a new study finds. PDX1, a transcription factor critical for pancreatic development, has distinct roles at different stages of pancreatic cancer – keeping cancer at bay in normal cells, then eventually contributing to the cancer’s growth […]
(SOURCE: JOHNS HOPKINS MEDICINE) – Epigenetic changes, not DNA mutations, drive some metastasis. A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates […]
(SOURCE: AMERICAN ASSOCIATION FOR CANCER RESEARCH) – The presence of circulating tumor DNA (ctDNA) isolated from blood samples of patients with pancreatic adenocarcinoma was associated with poor outcomes, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research. “Our study confirms, in one of the largest reported series, the […]
(SOURCE: STANFORD MEDICINE) Researchers at Stanford found that a new cell surface receptor they created is effective at inhibiting cancer growth in mice. A baseball glove is typically made from leather. If a new design made gloves more attractive to baseballs — catching them at higher rates than the typical glove — would it be a […]
(SOURCE: ROCKEFELLER UNIVERSITY PRESS) Conventional, high-dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors’ recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered. Frequent, low-dose chemotherapy regimens avoid this […]
(UNIVERSITY OF LIVERPOOL) According to a recent press release, a pioneering University of Liverpool research team have published a study that identifies the mechanism in the human body that causes resistance of pancreatic cancer cells to chemotherapy.
(UNIVERSITY OF NOTRE DAME) According to a recent press release, pancreatic cancer, the third leading cause of cancer-related deaths, is projected to be the second by the year 2030, according to a study in the journal of Cancer Research. The five-year survival rate is only 8 percent, making it the only major cancer with a […]
(THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE) According to a recent press release, The Translational Genomics Research Institute (TGen) has discovered potential drug targets to reduce pain in pancreatic cancer patients.
(UNIVERSITY OF ILLINOIS AT CHICAGO) According to a recent press release, researchers at the University of Illinois at Chicago have identified a new way to block the action of genetic mutations found in nearly 30 percent of all cancers.