Cholangiocarcinoma Symptoms, Causes and Treatment Information

What is Cholangiocarcinoma – CCA? (Definition)

(Symptoms, Causes & Treatment)

According to the U.S. National Library of Medicine, Cholangiocarcinoma (CCA) is a rare cancerous growth in one of the ducts that carries bile from the liver to the small intestine. Cholangiocarcinoma can start anywhere along the bile ducts. The condition mostly affects the elderly. People with certain health problems such as bile duct cysts, ulcerative colitis and other conditions may have a higher chance of developing cholangiocarcinoma.


Signs and Symptoms

Symptoms of CCA may include any combination of the following:

  • Fever and chills
  • Clay-colored stools and dark urine
  • Itching
  • Loss of appetite
  • Pain in the upper right abdomen that may radiate to the back
  • Weight loss
  • Jaundice

The exact cause of CCA isn’t known. However, many of these tumors are already quite advanced by the time they are found.

See below for updated news and information regarding Cholangiocarcinoma including new medical research, treatment options and advancements. 

Future of Global Bile Duct Cancer (Cholangiocarcinoma) Treatment

Medgadget (blog)14 hours ago
Bile duct cancer (cholangiocarcinoma) is the presence of mutated epithelial cells that originate in the bile ducts. Though, cause of bile duct …

FDA grants orphan drug designation to protein kinase CK2 inhibitor

HealioJan 10, 2017
The FDA has issued orphan drug designation to CX-4945 for the treatment of cholangiocarcinoma, which will expedite its development, the …

Report explores the bile duct cancer (cholangiocarcinoma

WhaTechJan 24, 2017
HTF Market Intelligence released a new research report of 492 pages on title ‘Bile Duct Cancer (Cholangiocarcinoma) – Pipeline Review, H2 …

BRIEF-Delcath announces patient treatment in intrahepatic

ReutersJan 12, 2017
BRIEF-Delcath announces patient treatment in intrahepatic Cholangiocarcinoma study. Jan 12 Delcath Systems Inc : * Delcath Systems Inc …

My Story with Cholangiocarcinoma

Curetoday.comSep 28, 2016
The word “cholangiocarcinoma” changed our lives forever, and I say “our” lives because cancer is not an individual diagnosis. Cancer instilled …

Latest Cholangiocarcinoma Research – Treatment News, Discoveries and Findings

No recent news regarding Cholangiocarcinoma is available. 

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Clinical Trials – Investigational Therapies

For information on current clinical trials, visit This is a searchable registry and results database of federally and privately supported clinical trials taking place in the U.S and abroad. provides information about a trial’s purpose, who may participate, locations, and phone numbers. This information should be used in conjunction with advice from health care professionals.

For information about clinical trials being conducted at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD, contact the NIH Patient Recruitment Office:

Toll Free: (800) 411-1222
TTY: (866) 411-1010

For information about clinical trials conducted in Europe, visit:

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