Chondrocalcinosis Symptoms, Causes and Treatment Information

What is Chondrocalcinosis? (Definition)

(Symptoms, Causes & Treatment)

Chondrocalcinosis is a generic term which refers to visible calcification of both hyaline cartilage and fibrocartilage. Chondrocalcinosis is frequently used to describe CPPD. Calcium pyrophosphate deposition disease (CPPD) is a very common cause of chondrocalcinosis. It is a rheumatologic disorder with varied symptoms and signs arising from the accumulation of crystals of calcium pyrophosphate dihydrate in the connective tissues. The alternative names emphasize particular aspects of the clinical or radiographic findings. The knee joint is the most commonly affected.

The exact cause of CPPD is unknown, although increased breakdown of adenosine triphosphate, which results in increased pyrophosphate levels in joints, is thought to be one reason why crystals may develop.


See below for updated news and information regarding Chondrocalcinosis including new medical research, treatment options and advancements. 

Latest Chondrocalcinosis Research – Treatment News, Discoveries and Findings

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Clinical Trials – Investigational Therapies

For information on current clinical trials, visit This is a searchable registry and results database of federally and privately supported clinical trials taking place in the U.S and abroad. provides information about a trial’s purpose, who may participate, locations, and phone numbers. This information should be used in conjunction with advice from health care professionals.

For information about clinical trials being conducted at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD, contact the NIH Patient Recruitment Office:

Toll Free: (800) 411-1222
TTY: (866) 411-1010

For information about clinical trials conducted in Europe, visit:

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