What is Dandy Walker Malformation – DWM (Syndrome)?
(Symptoms, Causes & Treatment)
Dandy Walker Syndrome is a rare group of congenital human brain malformations.
According to the U.S. Library of Medicine, Dandy-Walker malformation affects brain development, primarily development of the cerebellum (the part of the brain that coordinates movement). In people with this condition, various parts of the cerebellum develop abnormally, resulting in malformations that can be observed with medical imaging.
With Dandy Walker Syndrome, the central part of the cerebellum (the vermis) is absent or very small and may not be positioned correctly. The right and left sides of the cerebellum may be small as well. In affected individuals, a fluid-filled cavity between the brainstem and the cerebellum (the fourth ventricle) and the part of the skull that contains the cerebellum and the brainstem (the posterior fossa) are abnormally large. These abnormalities often result in problems with movement, coordination, intellect, mood, and other neurological functions.
Children with Dandy-Walker malformation often have delayed development, particularly a delay in motor skills such as crawling, walking, and coordinating movements. People with Dandy-Walker malformation may experience muscle stiffness and partial paralysis of the lower limbs (spastic paraplegia), and they may also have seizures. While rare, hearing and vision problems can be features of this condition.
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Latest Dandy Walker Malformation Treatment News and Research
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