What is Duane Syndrome? (Definition)
(Symptoms, Causes & Treatment)
According to Boston Children’s Hospital, Duane syndrome (also known as Duane’s syndrome or Duane retraction syndrome) is a relatively rare form of strabismus, or misalignment of the eye. Where most forms of strabismus leave side-to-side eye movements intact, in Duane syndrome the “wiring” of the eye muscles gets jumbled, and movement of eye(s) is limited in certain directions.
There are three types of Duane syndrome, but the most common is Type I, which interferes with the eye’s ability to move outward (away from the nose). Duane syndrome usually affects only one eye, but it can sometimes involve both. The left eye is more likely to be affected than the right, although doctors still don’t know exactly why.
What causes Duane syndrome?
The common thought is that Duane syndrome (DS) is a miswiring of the medial and the lateral rectus muscles, the muscles that move the eyes. Also, patients with DS lack the abducens nerve, the sixth cranial nerve, which is involved in eye movement. However, the etiology or origin of these malfunctions is, at present, a mystery.
Because the affected sixth cranial nerve cannot be repaired or replaced, there is no cure for Duane syndrome. However, for people whose lives are significantly disrupted by the condition, surgery can be very helpful in:
- reducing or stopping the abnormal head posture many develop in an attempt to see better
- reducing the angle of strabismus (misalignment of the eyes)
See below for updated news and information regarding Duane Syndrome including new medical research, treatment options and advancements.
Latest Duane Syndrome Research – Treatment News, Discoveries and Findings
No recent news regarding Duane Syndrome is available.
Clinical Resources: Treatment Therapies & Guidelines
Clinical Trials – Investigational Therapies
For information on current clinical trials, visit www.clinicaltrials.gov. This is a searchable registry and results database of federally and privately supported clinical trials taking place in the U.S and abroad. ClinicalTrials.gov provides information about a trial’s purpose, who may participate, locations, and phone numbers. This information should be used in conjunction with advice from health care professionals.
For information about clinical trials being conducted at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD, contact the NIH Patient Recruitment Office:
Toll Free: (800) 411-1222
TTY: (866) 411-1010
For information about clinical trials conducted in Europe, visit: https://www.clinicaltrialsregister.eu/ctr-search/search
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