What is Ovarian Cancer? (Definition)

According to The American Cancer Society, Ovarian cancer accounts for about 3% of cancers among women, but it causes more deaths than any other cancer of the female reproductive system. Ovarian cancer is a disease in which, depending on the type and stage of the disease, malignant (cancerous) cells are found inside, near, or on the outer layer of the ovaries. Ovarian cancer is difficult to detect, especially, in the early stages.


Signs and Symptoms of Ovarian Cancer

Ovarian cancer may cause several signs and symptoms. Women are more likely to have symptoms if the disease has spread beyond the ovaries, but even early- stage ovarian cancer can cause them.

  • Bloating
  • Fatigue
  • Pelvic or abdominal pain
  • Back pain
  • Trouble eating or feeling full quickly
  • Feeling the need to urinate urgently or often
  • Other symptoms of ovarian cancer can include:
  • Upset stomach or heartburn
  • Pain during sex
  • Constipation or menstrual changes

See below for updated news and information regarding Ovarian Cancer including new medical research, treatment options and advancements. 

Latest Ovarian Cancer News

Screening with frequent personalized CA125 testing may improve detection of ovarian cancer in high-risk women

(SOURCE: MASSACHUSETTS GENERAL HOSPITAL) - The combined results of two ovarian cancer screening trials suggest that a personalized strategy involving frequent screening of high-risk women could improve the chance that tumors are detected at early stages when they are easier to treat. As reported in a paper published in Clinical Cancer Research, these trials imply that a protocol involving quarterly blood testing ...
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Ovarian Cancer Treatment News: Murine study finds potential boost for ovarian cancer drug Olaparib

(SOURCE: ROCKEFELLER UNIVERSITY PRESS) - Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza). Their findings in the study "Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells," which has ...
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Ovarian Cancer Treatment News: New test could detect ovarian cancer patients who are strongly responding to treatment

(SOURCE: CANCER RESEARCH UK) - Scientists might be able to quickly predict how ovarian cancer patients are likely to respond to chemotherapy treatment using a simple blood test, according to a Cancer Research UK-funded study published in PLOS Medicine. In a study of 40 patients with high grade serous ovarian cancer, the researchers monitored tumour DNA that could be detected in ...
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Enzyme that regulates DNA repair may offer new precision treatments for breast and ovarian cancer

(SOURCE: MAYO CLINIC) Researchers at Mayo Clinic have identified an enzyme called UCHL3 that regulates the BRCA2 pathway, which is important for DNA repair. Results of this research are published online in Genes & Development. “DNA encodes the blueprints for our body, and DNA repair is a fundamental mechanism to prevent the accumulation of mutations in DNA and human disease,” says ...
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Cancer Treatment Research: Researchers develop new compound to reduce tumor growth

(SOURCE: STANFORD MEDICINE) Researchers at Stanford found that a new cell surface receptor they created is effective at inhibiting cancer growth in mice. A baseball glove is typically made from leather. If a new design made gloves more attractive to baseballs — catching them at higher rates than the typical glove — would it be a game changer? Researchers at Stanford ...
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Yale Researchers Identify Genes Behind Ovarian and Endometrial Cancers

(Yale) According to a recent article published in Yale News, in a major breakthrough for ovarian and uterine cancers, Yale researchers have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas (CSs), pointing the way to possible new treatments ...
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Ovarian Cancer News: Study Finds that a Combination Therapy improves Chemoresistance

(THE WISTAR INSTITUTE) According to a recent press release, treating ovarian cancer with platinum-based chemotherapy drugs such as cisplatin is initially very effective, with about four out of five patients responding favorably. However, most of these patients quickly become resistant to chemotherapy and may not respond as well to this standard treatment for the disease ...
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New Research Unveils Possible New Treatment Option for Ovarian Cancer

(BOSTON UNIVERSITY MEDICAL CENTER) According to an article recently published by Boston University Medical Center, a new study has identified an effective combination therapy for treating ovarian cancer cells ...
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Experimental Immunotherapy Galinpepimut-S May Benefit Multiple Myeloma Patients

(Myeloma Research News) According to a recent article published Myeloma Research News, patients with high-risk multiple myeloma may benefit from an experimental immunotherapy from SELLAS Life Sciences called galinpepimut-S, following an autologous stem cell transplant (ASCT). The data was gathered from a Phase 2 clinical trial which shows that the agent nearly doubles the progression-free survival rates compared to historical controls who ...
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Oxford Gene Technology Simplifies Detection of Important Cancer Gene Variants

(PR Newswire) Oxford Gene Technology (OGT), The Molecular Genetics Company, has launched its SureSeq myPanel™ NGS Custom Cancer Panels to provide scientists with completely customized, pre-optimized next generation sequencing (NGS) probe panels relevant to their research. The comprehensive library of gene content covers key cancer types including, myeloid, chronic lymphocytic leukemia (CLL), ovarian and breast. Utilizing hybridisation-based capture, the panels deliver unparalleled coverage ...
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