Acanthosis nigricans (AN) is a condition affecting the skin which is identified by abnormal coloration or hyperpigmentation and thickening (hyperkeratosis) of the skin The condition is most often found in skin fold regions, such as of the neck and groin and under the arms (axillae). Various benign (non-cancerous) forms of AN have been identified in which the disorder may be inherited as a primary condition or associated with various underlying syndromes, an excess accumulation of body fat (obesity), or the use of certain medications (i.e., drug-induced AN). In other instances, AN may occur in association with an underlying cancerous tumor (i.e., malignant AN).
Acanthosis Nigricans Signs and Symptoms
Skin changes are the only signs of acanthosis nigricans that you will likely see. You’ll notice dark, thickened, velvety skin in body folds and creases — typically in your armpits, groin and back of the neck. The skin changes usually appear slowly. The affected skin may also have an odor or itch.
Acanthosis Nigricans News and Information
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