Acquired Hemophilia News and Information

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Acquired hemophilia (AH) is a rare autoimmune disorder recognized by bleeding that occurs in patients with a personal and family history negative for hemorrhages. Autoimmune disorders occur when the body’s immune system mistakenly attacks healthy cells or tissue. Acquired hemophilia shares some similarities with congenital hemophilia but is a distinctly different condition. Normally, blood clots after injury or surgical procedures by a complicated process involving a number of different proteins. These are mostly made in the liver and then released into the blood.

In acquired hemophilia, the person may not have a history of bleeding. At some point in their life their immune system develops an antibody to their own factor VIII – this antibody stops FVIII working normally and removes it from the circulation. This lack of factor VIII activity is why these patients bleed; sometimes this bleeding is in response to trauma, and sometimes patients will bleed for no apparent reason.

In about half the cases of acquired hemophilia that are diagnosed, the cause is never established. Part of the immune system becomes over-active towards Factor VIII.

Acquired Hemophilia News and Information

See below for updated news and information regarding Acquired Hemophilia including new research, treatments and advancements. 

Latest Acquired Hemophilia News

Blood Thinner Linked to Onset of Acquired Hemophilia A in Heart

Hemophilia News TodayOct 5, 2016
Treatments with anti-coagulation drugs such as Brilinta (ticagrelor) may trigger acquired Hemophilia A (AHA) in adults. This finding was …

Case Report: Acquired Hemophilia A with Bone Marrow Disorder

Hemophilia News TodayAug 11, 2016
“Myelofibrosis and acquired hemophilia A: a case report,” published in the Journal of Medical Case Reports, is only the second in published …